The mammalian circadian clock exerts control of daily gene expression through cycles of DNA binding.Here, we develop a quantitative model of Rocking Chair how a finite pool of BMAL1 protein can regulate thousands of target sites over daily time scales.We used quantitative imaging to track dynamic changes in endogenous labelled proteins across perip
Problems related to the use of animals for therapeutic and care purposes: the document of the National Committee for Bioethics
The Italian Ministry of Health, in 2002, instructed the National Committee for Bioethics to Bosch GIN81AE30G Freezer A++ Rating in White Built-In/Integrated carefully review and ultimately provide evidence for future legislative bills in various aspects.One such matter was that of the subject of "Pet Therapy", generically viewed as a "man-animal" r
Study of the probability of resistance to phage infection in a collection of clinical isolates of Pseudomonas aeruginosa in relation to the presence of Pf phages
ABSTRACT Pseudomonas aeruginosa is a bacterial pathogen that is a major cause of lung infections in cystic fibrosis (CF) and other patients.Isolates of P.aeruginosa from CF patients commonly carry filamentous phages (Pf phages), which constitute a family of temperate phages known to be related to biofilm production and antibiotic sequestration.In t
Treatment of recurrent aphthous stomatitis major with metronidazole and ciprofloxacin
Background: Recurrent aphthous stomatitis (RAS) are painful oral ulcerations that recur from days to months or even years.It represents the most common lesion of the oral mucosa with prevalence ranging from 15% to 30%.Although the clinical characteristics of RAS are well defined, the Neff KI1413FF0 N70 In-column Integrated Fridge With FreshSafe pre
Energy geostructures: Theory and application
The subsurface represents space and resource of ever-growing importance to meet human activity needs associated with the availability of built environments and energy.So-called energy geostructures represent a breakthrough technology in this context.By integrating the structural support role of earth-contact structures with the heating-cooling role